Lectures

Ischemic heart disease

Author: Jana Plevková

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Clinical stand point – classification. Coronary circulation. Regulation of coronary circulation. Myocardial ischemia. Endothelial vasodilatators. A new insight into atherosclerosis. Progression of ATS process. Progression in the plaque growing. Nonstable plaque. Thrombosis inside the CA. Development of ischemic injury of myocardium. Electrophysiological changes. Mechanical properties. Clinical signs of IHD. Myocardial enzymes...

Radioactivity and ionizing radiation

Author: Ivan Poliaček

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The aims of the lecture

  • atomic structure
  • ionization
  • ionization vs. excitation (low vs. high energy photon)
  • production of ionizing radiation
  • basic particles and their properties
  • mechanisms of interaction
  • basic units
  • basics of the damage of biological material

 

Biophysics Of Muscle Contraction

Author: Ivan Poliaček, Ján Jakuš

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Basic muscle properties,.Sceletal, cardiac, smooth muscles and the differences. Basic muscle and muscle cell structure (myofibril, sarcomere, actin, myosin...). Motor unit, neuro-muscular junction, acetylcholine, end-plate potential. T tubules, sarcoplasmic reticulum, muscle fiber action potential. Muscle contraction and its control (tropomyosin), role of Ca ions and ATP. Single muscle twitch, superposition, summation, tetanus (unfused, fused), rigor mortis. Single unit and multiunit smooth muscle, gap junction, syncytium. Cardiac muscle structure, intercalated discs, Ca induced Ca release. Cardiac muscle action potential, the duration of action potential, summation of contraction.

Biophysics Of Action Potential & Synapse

Author: Ivan Poliaček, Ján Jakuš

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Depolarization, repolarization, hyperpolarization, action potential – the shape, mechanisms, refractory periods, propagation of action potential (continual spreading, saltatory conduction), electrical stimulation – rheobase, chronaxy, graded potential, synapse, neurotransmitter, mechanisms of transmission receptors (ionotropic vs. metabotropic), EPSP, IPSP, summation (temporal, spatial), convergence, divergence.

Introduction to General Anesthesiology

Author: Miroslav Šulaj

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Introduction to General Anesthesiology for 3rd VLs - Location: Faculty Hospital small lecture hall, live videoconference from operating room for surgery February 12, 2008 at 8:00am